There are 55 published clinical (human) studies on K2 according to a Pubmed search. Best to our knowledge, all of them are sponsored and published by academia bodies, not private companies. Some of our competitors provided technical assistance and free placebo and active samples in some of these studies (Collaborators). Please see the list of clinical trials with their sponsors and collaborators from this reliable source.
The results of these studies are copyrighted, however quoting small sections that are directly relevant to something one is writing about is acceptable under Fair Use, as long as one provides an appropriate citation. Summarizing and quoting from a medical article in a news article (Commentary, Criticism, “transformative”purpose) is considered a fair use according to this source. All human clinical studies were designed and performed on Menaquinone-7 chemical compound which does not differ in terms of bioavailability or safety profile regardless if obtained through organic synthesis or biochemistry (industrial fermentation). Vitamin K2 offered in the market differs only in terms of purity offered and presentation oil, powder, microcapsule. We encourage all our clients to produce educational content based on the available study results and fair use policy. In case of advertising of a specific brand, use of third-party study results is prohibited.
Read more...
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
TITLE
Vitamin K supplementation and bone mineral density in dialysis: results of the double-blind, randomized, placebo-controlled RenaKvit trial.
AUTHORS
Levy-Schousboe K, Marckmann P, Frimodt-Moller M, Peters CD, Kjaergaard KD, Jensen JD, Strandhave C, Sandstrom H, Hitz MF, Langdahl B, Vestergaard P, Brasen CL, Schmedes A, Madsen JS, Jorgensen NR, Frokjaer JB, Frandsen NE, Petersen I, Hansen D
CATEGORY
Cardiovascular Health
DATE
Sep 2023
KEYWORDS
bone mineral density, chronic kidney disease, end-stage kidney disease, menaquinone-7, mineral and bone disorder
Effect of vitamin K supplementation on serum calcification propensity and arterial stiffness in vitamin K-deficient kidney transplant recipients: A double-blind, randomized, placebo-controlled clinical trial.
AUTHORS
Eelderink C, Kremer D, Riphagen IJ, Knobbe TJ, Schurgers LJ, Pasch A, Mulder DJ, Corpeleijn E, Navis G, Bakker SJL, de Borst MH, Te Velde-Keyzer CA
The effect of menaquinone-7 supplementation on dp-ucMGP, PIVKAII, inflammatory markers, and body composition in type 2 diabetes patients: a randomized clinical trial.
AUTHORS
Karamzad N, Faraji E, Adeli S, Sullman MJM, Pourghassem Gargari B
Vitamin K2 (menaquinone-7) increases plasma adiponectin but does not affect insulin sensitivity in postmenopausal women: a randomized controlled trial.
The effect of menaquinone-7 supplementation on vascular calcification in patients with diabetes: a randomized, double-blind, placebo-controlled trial.
AUTHORS
Zwakenberg SR, de Jong PA, Bartstra JW, van Asperen R, Westerink J, de Valk H, Slart RHJA, Luurtsema G, Wolterink JM, de Borst GJ, van Herwaarden JA, van de Ree MA, Schurgers LJ, van der Schouw YT, Beulens JWJ
CATEGORY
Cardiovascular Health
DATE
Oct 2019
KEYWORDS
cardiovascular disease, diabetes, menaquinone-7, vascular calcification, vitamin K
Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using (18)F-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design.
Fecal concentrations of bacterially derived vitamin K forms are associated with gut microbiota composition but not plasma or fecal cytokine concentrations in healthy adults.
AUTHORS
Karl JP, Meydani M, Barnett JB, Vanegas SM, Barger K, Fu X, Goldin B, Kane A, Rasmussen H, Vangay P, Knights D, Jonnalagadda SS, Saltzman E, Roberts SB, Meydani SN, Booth SL
Menaquinone-7 Supplementation to Reduce Vascular Calcification in Patients with Coronary Artery Disease: Rationale and Study Protocol (VitaK-CAC Trial).
AUTHORS
Vossen LM, Schurgers LJ, van Varik BJ, Kietselaer BL, Vermeer C, Meeder JG, Rahel BM, van Cauteren YJ, Hoffland GA, Rennenberg RJ, Reesink KD, de Leeuw PW, Kroon AA
Association of vitamin K status with adiponectin and body composition in healthy subjects: uncarboxylated osteocalcin is not associated with fat mass and body weight.
AUTHORS
Knapen MH, Schurgers LJ, Shearer MJ, Newman P, Theuwissen E, Vermeer C
CATEGORY
Clinical Trials
DATE
Sep 2012
KEYWORDS
body fat, body weight, menaquinone-4, menaquinone-7, postmenopausal women, vitamin K2
Possible site-specific effect of an intervention combining nutrition and lifestyle counselling with consumption of fortified dairy products on bone mass: the Postmenopausal Health Study II.
AUTHORS
Moschonis G, Kanellakis S, Papaioannou N, Schaafsma A, Manios Y
CATEGORY
Postmenopausal Women
DATE
Jul 2011
KEYWORDS
bone mineral density, calcium, menaquinone-7, phylloquinone, postmenopausal women, vitamin D3, vitamin K1, vitamin K2
Vitamin K treatment reduces undercarboxylated osteocalcin but does not alter bone turnover, density, or geometry in healthy postmenopausal North American women.
AUTHORS
Binkley N, Harke J, Krueger D, Engelke J, Vallarta-Ast N, Gemar D, Checovich M, Chappell R, Suttie J
CATEGORY
Bone Health
DATE
Jun 2009
KEYWORDS
bone health, menaquinone-4, phylloquinone, postmenopausal women, vitamin K1, vitamin K2
Excretion of the urinary 5C- and 7C-aglycone metabolites of vitamin K by young adults responds to changes in dietary phylloquinone and dihydrophylloquinone intakes.
AUTHORS
Harrington DJ, Booth SL, Card DJ, Shearer MJ
CATEGORY
Bone Health
DATE
Jul 2007
KEYWORDS
phylloquinone, urinary excretion of vitamin K metabolites, vitamin K1
Inverse correlation between the changes of lumbar bone mineral density and serum undercarboxylated osteocalcin after vitamin K2 (menatetrenone) treatment in children treated with glucocorticoid and alfacalcidol.
AUTHORS
Inoue T, Sugiyama T, Matsubara T, Kawai S, Furukawa S
Intake of fermented soybean (natto) increases circulating vitamin K2 (menaquinone-7) and gamma-carboxylated osteocalcin concentration in normal individuals.
