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There are 55 published clinical (human) studies on K2 according to a Pubmed search. Best to our knowledge, all of them are sponsored and published by academia bodies, not private companies. Some of our competitors provided technical assistance and free placebo and active samples in some of these studies (Collaborators). Please see the list of clinical trials with their sponsors and collaborators from this reliable source.
The results of these studies are copyrighted, however quoting small sections that are directly relevant to something one is writing about is acceptable under Fair Use, as long as one provides an appropriate citation. Summarizing and quoting from a medical article in a news article (Commentary, Criticism, “transformative”purpose) is considered a fair use according to this source.
All human clinical studies were designed and performed on Menaquinone-7 chemical compound which does not differ in terms of bioavailability or safety profile regardless if obtained through organic synthesis or biochemistry (industrial fermentation). Vitamin K2 offered in the market differs only in terms of purity offered and presentation oil, powder, microcapsule.
We encourage all our clients to produce educational content based on the available study results and fair use policy. In case of advertising of a specific brand, use of third-party study results is prohibited.
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TITLE
Vitamin K supplementation and bone mineral density in dialysis: results of the double-blind, randomized, placebo-controlled RenaKvit trial.
AUTHORS
Levy-Schousboe K, Marckmann P, Frimodt-Moller M, Peters CD, Kjaergaard KD, Jensen JD, Strandhave C, Sandstrom H, Hitz MF, Langdahl B, Vestergaard P, Brasen CL, Schmedes A, Madsen JS, Jorgensen NR, Frokjaer JB, Frandsen NE, Petersen I, Hansen D
CATEGORY
Cardiovascular Health
DATE
Sep 2023
KEYWORDS
bone mineral density, chronic kidney disease, end-stage kidney disease, menaquinone-7, mineral and bone disorder
PUBMED LINK
TITLE
Vitamin K2 and D in Patients With Aortic Valve Calcification: A Randomized Double-Blinded Clinical Trial.
AUTHORS
Diederichsen ACP, Lindholt JS, Moller S, Ovrehus KA, Auscher S, Lambrechtsen J, Hosbond SE, Alan DH, Urbonaviciene G, Becker SW, Fredgart MH, Hasific S, Folkestad L, Gerke O, Rasmussen LM, Moller JE, Mickley H, Dahl JS
CATEGORY
Cardiovascular Health
DATE
May 2022
KEYWORDS
aortic valve calcification, aortic valve stenosis, coronary artery calcification, coronary artery disease, matrix Gla protein, randomized controlled trial, vitamin K2
PUBMED LINK
TITLE
The effect of menaquinone-7 supplementation on vascular calcification in patients with diabetes: a randomized, double-blind, placebo-controlled trial.
AUTHORS
Zwakenberg SR, de Jong PA, Bartstra JW, van Asperen R, Westerink J, de Valk H, Slart RHJA, Luurtsema G, Wolterink JM, de Borst GJ, van Herwaarden JA, van de Ree MA, Schurgers LJ, van der Schouw YT, Beulens JWJ
CATEGORY
Cardiovascular Health
DATE
Oct 2019
KEYWORDS
cardiovascular disease, diabetes, menaquinone-7, vascular calcification, vitamin K
PUBMED LINK
TITLE
Vitamin K-induced effects on body fat and weight: results from a 3-year vitamin K2 intervention study.
AUTHORS
Knapen MHJ, Jardon KM, Vermeer C
CATEGORY
Cardiovascular Health
DATE
Jan 2018
KEYWORDS
body fat, body weight, menaquinone-7, postmenopausal women, vitamin K2
PUBMED LINK
TITLE
Vitamin K2 (menaquinone-7) prevents age-related deterioration of trabecular bone microarchitecture at the tibia in postmenopausal women.
AUTHORS
Ronn SH, Harslof T, Pedersen SB, Langdahl BL
CATEGORY
Cardiovascular Health
DATE
Dec 2016
KEYWORDS
bone mineral density, calcium, menaquinone-7, osteopenia, postmenopausal women, vitamin D, vitamin K2
PUBMED LINK
TITLE
Menaquinone-7 Supplementation to Reduce Vascular Calcification in Patients with Coronary Artery Disease: Rationale and Study Protocol (VitaK-CAC Trial).
AUTHORS
Vossen LM, Schurgers LJ, van Varik BJ, Kietselaer BL, Vermeer C, Meeder JG, Rahel BM, van Cauteren YJ, Hoffland GA, Rennenberg RJ, Reesink KD, de Leeuw PW, Kroon AA
CATEGORY
Cardiovascular Health
DATE
Oct 2015
KEYWORDS
coronary artery calcification, matrix gla protein, menaquinone-7, vascular calcification, vitamin K2
PUBMED LINK
TITLE
Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial.
AUTHORS
Knapen MH, Braam LA, Drummen NE, Bekers O, Hoeks AP, Vermeer C
CATEGORY
Cardiovascular Health
DATE
May 2015
KEYWORDS
Arterial stiffness, Stiffness Index beta, carotid intima-media thickness, menaquinone-7, pulse wave velocity
PUBMED LINK
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