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There are 55 published clinical (human) studies on K2 according to a Pubmed search. Best to our knowledge, all of them are sponsored and published by academia bodies, not private companies. Some of our competitors provided technical assistance and free placebo and active samples in some of these studies (Collaborators). Please see the list of clinical trials with their sponsors and collaborators from this reliable source.
The results of these studies are copyrighted, however quoting small sections that are directly relevant to something one is writing about is acceptable under Fair Use, as long as one provides an appropriate citation. Summarizing and quoting from a medical article in a news article (Commentary, Criticism, “transformative”purpose) is considered a fair use according to this source.
All human clinical studies were designed and performed on Menaquinone-7 chemical compound which does not differ in terms of bioavailability or safety profile regardless if obtained through organic synthesis or biochemistry (industrial fermentation). Vitamin K2 offered in the market differs only in terms of purity offered and presentation oil, powder, microcapsule.
We encourage all our clients to produce educational content based on the available study results and fair use policy. In case of advertising of a specific brand, use of third-party study results is prohibited.
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TITLE
Effect of Low-Dose Vitamin K2 Supplementation on Bone Mineral Density in Middle-Aged and Elderly Chinese: A Randomized Controlled Study.
AUTHORS
Zhang Y, Liu Z, Duan L, Ji Y, Yang S, Zhang Y, Li H, Wang Y, Wang P, Chen J, Li Y
CATEGORY
Osteoporosis
DATE
May 2020
KEYWORDS
Bone mineral density, Menaquinone-7, Osteoporosis, Postmenopausal women, Vitamin K2
PUBMED LINK
TITLE
Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women.
AUTHORS
Knapen MH, Drummen NE, Smit E, Vermeer C, Theuwissen E
CATEGORY
Osteoporosis
DATE
Sep 2013
KEYWORDS
bone loss, bone mineral density, menaquinone-7, postmenopausal women, vitamin K2
PUBMED LINK
TITLE
Vitamin K2 supplementation does not influence bone loss in early menopausal women: a randomised double-blind placebo-controlled trial.
AUTHORS
Emaus N, Gjesdal CG, Almas B, Christensen M, Grimsgaard AS, Berntsen GK, Salomonsen L, Fonnebo V
CATEGORY
Osteoporosis
DATE
Oct 2010
KEYWORDS
bone loss, early menopausal women, menaquinone-7, vitamin K2
PUBMED LINK
TITLE
Effect of low dose vitamin K2 (MK-4) supplementation on bio-indices in postmenopausal Japanese women.
AUTHORS
Koitaya N, Ezaki J, Nishimuta M, Yamauchi J, Hashizume E, Morishita K, Miyachi M, Sasaki S, Ishimi Y
CATEGORY
Osteoporosis
DATE
Feb 2009
KEYWORDS
bone metabolism, menaquinone-4, postmenopausal women, vitamin K2
PUBMED LINK
TITLE
Vitamin K(2) (menaquinone 4) reduces serum undercarboxylated osteocalcin level as early as 2 weeks in elderly women with established osteoporosis.
AUTHORS
Miki T, Nakatsuka K, Naka H, Kitatani K, Saito S, Masaki H, Tomiyoshi Y, Morii H, Nishizawa Y
CATEGORY
Osteoporosis
DATE
Jan 2003
KEYWORDS
bone metabolism, calcium, menaquinone-4, osteoporosis, vitamin K2
PUBMED LINK
TITLE
Vitamin K administration to elderly patients with osteoporosis induces no hemostatic activation, even in those with suspected vitamin K deficiency.
AUTHORS
Asakura H, Myou S, Ontachi Y, Mizutani T, Kato M, Saito M, Morishita E, Yamazaki M, Nakao S
CATEGORY
Osteoporosis
DATE
Dec 2001
KEYWORDS
hemostatic balance, menaquinone-4, osteoporosis, vitamin K2
PUBMED LINK
TITLE
Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis.
AUTHORS
Shiraki M, Shiraki Y, Aoki C, Miura M
CATEGORY
Osteoporosis
DATE
Mar 2000
KEYWORDS
bone mineral density, menaquinone-4, osteoporosis, vitamin K2
PUBMED LINK
TITLE
Menatetrenone ameliorates osteopenia in disuse-affected limbs of vitamin D- and K-deficient stroke patients.
AUTHORS
Sato Y, Honda Y, Kuno H, Oizumi K
CATEGORY
Osteoporosis
DATE
Sep 1998
KEYWORDS
bone mineral density, menaquinone-4, phylloquinone, vitamin K1, vitamin K2
PUBMED LINK
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