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There are 55 published clinical (human) studies on K2 according to a Pubmed search. Best to our knowledge, all of them are sponsored and published by academia bodies, not private companies. Some of our competitors provided technical assistance and free placebo and active samples in some of these studies (Collaborators). Please see the list of clinical trials with their sponsors and collaborators from this reliable source.
The results of these studies are copyrighted, however quoting small sections that are directly relevant to something one is writing about is acceptable under Fair Use, as long as one provides an appropriate citation. Summarizing and quoting from a medical article in a news article (Commentary, Criticism, “transformative”purpose) is considered a fair use according to this source.
All human clinical studies were designed and performed on Menaquinone-7 chemical compound which does not differ in terms of bioavailability or safety profile regardless if obtained through organic synthesis or biochemistry (industrial fermentation). Vitamin K2 offered in the market differs only in terms of purity offered and presentation oil, powder, microcapsule.
We encourage all our clients to produce educational content based on the available study results and fair use policy. In case of advertising of a specific brand, use of third-party study results is prohibited.
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TITLE
Effect of Menaquinone-7 Supplementation on Arterial Stiffness in Chronic Hemodialysis Patients: A Multicenter Randomized Controlled Trial.
AUTHORS
Naiyarakseree N, Phannajit J, Naiyarakseree W, Mahatanan N, Asavapujanamanee P, Lekhyananda S, Vanichakarn S, Avihingsanon Y, Praditpornsilpa K, Eiam-Ong S, Susantitaphong P
CATEGORY
Clinical Trials
DATE
May 2023
KEYWORDS
arterial stiffness, carotid-femoral pulse wave velocity, chronic hemodialysis, menaquinone-7
PUBMED LINK
TITLE
Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using (18)F-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design.
AUTHORS
Peeters FECM, van Mourik MJW, Meex SJR, Bucerius J, Schalla SM, Gerretsen SC, Mihl C, Dweck MR, Schurgers LJ, Wildberger JE, Crijns HJGM, Kietselaer BLJH
CATEGORY
Clinical Trials
DATE
Mar 2018
KEYWORDS
18F-NaF, PET/MR, bicuspid aortic valve, calcific aortic valve stenosis, menaquinone-7, vitamin K2
PUBMED LINK
TITLE
Steady-state vitamin K2 (menaquinone-7) plasma concentrations after intake of dairy products and soft gel capsules.
AUTHORS
Knapen MH, Braam LA, Teunissen KJ, Van't Hoofd CM, Zwijsen RM, van den Heuvel EG, Vermeer C
CATEGORY
Clinical Trials
DATE
Jul 2016
KEYWORDS
menaquinone-7, postmenopausal women, vitamin K intake, vitamin K2, vitamin absorption
PUBMED LINK
TITLE
Menaquinone-7 as a novel pharmacological therapy in the treatment of rheumatoid arthritis: A clinical study.
AUTHORS
Abdel-Rahman MS, Alkady EA, Ahmed S
CATEGORY
Clinical Trials
DATE
Aug 2015
KEYWORDS
DAS28-ESR, Matrix metalloproteinase., Menaquinone-7, Rheumatoid arthritis, ucOC
PUBMED LINK
TITLE
Low-dose menaquinone-7 supplementation improved extra-hepatic vitamin K status, but had no effect on thrombin generation in healthy subjects.
AUTHORS
Theuwissen E, Cranenburg EC, Knapen MH, Magdeleyns EJ, Teunissen KJ, Schurgers LJ, Smit E, Vermeer C
CATEGORY
Clinical Trials
DATE
Nov 2012
KEYWORDS
carboxylation, menaquinone-7, vitamin K2
PUBMED LINK
TITLE
Comparison of menaquinone-4 and menaquinone-7 bioavailability in healthy women.
AUTHORS
Sato T, Schurgers LJ, Uenishi K
CATEGORY
Clinical Trials
DATE
Nov 2012
KEYWORDS
menaquinone-4, menaquinone-7, vitamin K2, vitamin bioavailability
PUBMED LINK
TITLE
Association of vitamin K status with adiponectin and body composition in healthy subjects: uncarboxylated osteocalcin is not associated with fat mass and body weight.
AUTHORS
Knapen MH, Schurgers LJ, Shearer MJ, Newman P, Theuwissen E, Vermeer C
CATEGORY
Clinical Trials
DATE
Sep 2012
KEYWORDS
body fat, body weight, menaquinone-4, menaquinone-7, postmenopausal women, vitamin K2
PUBMED LINK
TITLE
Effect of vitamin K2 supplementation on functional vitamin K deficiency in hemodialysis patients: a randomized trial.
AUTHORS
Westenfeld R, Krueger T, Schlieper G, Cranenburg EC, Magdeleyns EJ, Heidenreich S, Holzmann S, Vermeer C, Jahnen-Dechent W, Ketteler M, Floege J, Schurgers LJ
CATEGORY
Clinical Trials
DATE
Feb 2012
KEYWORDS
menaquinone-7, vascular calcification, vitamin K deficiency, vitamin K2
PUBMED LINK
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